Identification of atypical El Tor V-cholerae O1 Ogawa hosting SXT element in Senegal, Africa Sambe-Ba, B. Diallo, M. H. Seck, A. Wane, A. A. /Constantin de Magny, Guillaume Boye, C. S. B. Sow, A. I. Gassama-Sow, A. Vibrio cholerae O1 virulence antibioresistance SXT element Senegal Vibrio cholerae O1 is the causative agent of cholera with classical and El Tor, two well-established biotypes. In last 20 years, hybrid strains of classical and El Tor and variant El Tor which carry classical ctxB have emerged worldwide. In 2004-2005, Senegal experienced major cholera epidemic with a number of cases totalling more than 31719 with approximately 458 fatal outcomes (CFR, 1.44%). In this retrospective study, fifty isolates out of a total of 403 V. cholerae biotype El Tor serovar Ogawa isolates from all areas in Senegal during the 2004-2005 cholera outbreak were randomly selected. Isolates were characterized using phenotypic and genotypic methods. The analysis of antibiotic resistance patterns revealed the predominance of the S-Su-TCY-Tsu phenotype (90% of isolates). The molecular characterization of antibiotic resistance revealed the presence of the SXT element, a self-transmissible chromosomally integrating element in all isolates. Most of V. cholerae isolates had an intact virulence cassette (86%) (ctx, zot, ace genes). All isolates tested gave amplification with primers for classical CT, and 10/50 (20%) of isolates carried classical and El Tor ctxB. The study reveals the presence of atypical V. cholerae O1 El Tor during cholera outbreak in Senegal in 2004-2005. 2017 text https://www.documentation.ird.fr/hor/fdi:010070052 fdi:010070052 Sambe-Ba B., Diallo M. H., Seck A., Wane A. A., Constantin de Magny Guillaume, Boye C. S. B., Sow A. I., Gassama-Sow A.. Identification of atypical El Tor V-cholerae O1 Ogawa hosting SXT element in Senegal, Africa. 2017, 8, art. 748 [7 p.] EN SENEGAL