Vieira C. auteur aut IRD Gaubert J. auteur aut IRD De Clerck O. auteur aut IRD Payri Claude auteur aut IRD Culioli G. auteur aut IRD Thomas O. P. auteur aut IRD text journalArticle eng text/pdf born digital access Although Lobophora belongs to a marine algal family (Dictyotaceae) that produces a large array of secondary metabolites, it has received little attention compared to other genera, such as Dictyota, in terms of natural compounds isolation and characterization. However, metabolites produced by Lobophora species have been found to exhibit a wide array of bioactivities including pharmacological (e.g. antibacterial, antiviral, antioxidant, antitumoral), pesticidal, and ecological. This review aims to report the state-of-the-art of the natural products isolated from Lobophora species (Dictyotales, Phaeophyceae) and their associated bioactivities. All bioactivities documented in the literature are reported, therefore including studies for which pure active substances were described, as well as studies limited to extracts or fractions. From the early 1980s until today, 49 scientific works have been published on Lobophora chemistry and bioactivity, among which 40 have reported bioactivities. Only six studies, however, have identified, characterized and tested no less than 23 bioactive pure compounds (three C-21 polyunsaturated alcohols, three fatty-acids, a macrolactone, 11 polyketides, a few sulfated polysaccharides, three sulfolipids, a tocopherol derivative). The present review intends to raise awareness of chemists and biologists given the recent significant taxonomic progress of this brown algal genus, which holds a promising plethora of natural products yet to be discovered with ecological and pharmacological properties. specialized Bioactivity Brown algae Lobophora Natural products 035 16 1 1-17 2017 1568-7767 https://www.documentation.ird.fr/hor/fdi:010069445 10.1007/s11101-015-9445-x 1568-7767 [F B010069445] https://www.documentation.ird.fr/hor/fdi:010069445 https://www.documentation.ird.fr/intranet/publi/2017/04/010069445.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2017-05-09 2023-07-11 fdi:010069445 fre