@article{fdi:010068994,
  title = {{C}ancer brings forward oviposition in the fly {D}rosophila melanogaster},
  author = {{A}rnal, {A}. and {J}acqueline, {C}. and {U}javari, {B}. and {L}eger, {L}. and {M}oreno, {C}. and {F}augere, {D}. and {T}asiemski, {A}. and {B}oidin-{W}ihlaz, {C}. and {M}iss{\'e}, {D}oroth{\'e}e and {R}enaud, {F}. and {M}ontagne, {J}. and {C}asali, {A}. and {R}oche, {B}enjamin and {M}ery, {F}. and {T}homas, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}osts often accelerate their reproductive effort in response to a parasitic infection, especially when their chances of future reproduction decrease with time from the onset of the infection. {B}ecause malignancies usually reduce survival, and hence potentially the fitness, it is expected that hosts with early cancer could have evolved to adjust their life-history traits to maximize their immediate reproductive effort. {D}espite the potential importance of these plastic responses, little attention has been devoted to explore how cancers influence animal reproduction. {H}ere, we use an experimental setup, a colony of genetically modified flies {D}rosophila melanogaster which develop colorectal cancer in the anterior gut, to show the role of cancer in altering life-history traits. {S}pecifically, we tested whether females adapt their reproductive strategy in response to harboring cancer. {W}e found that flies with cancer reached the peak period of oviposition significantly earlier (i.e., 2 days) than healthy ones, while no difference in the length and extent of the fecundity peak was observed between the two groups of flies. {S}uch compensatory responses to overcome the fitness-limiting effect of cancer could explain the persistence of inherited cancer-causing mutant alleles in the wild.},
  keywords = {},
  booktitle = {},
  journal = {{E}cology and {E}volution},
  volume = {7},
  numero = {1},
  pages = {272--276},
  ISSN = {2045-7758},
  year = {2017},
  DOI = {10.1002/ece3.2571},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068994},
}