Wichit S. auteur aut IRD Ferraris Pauline auteur aut IRD Choumet V. auteur aut IRD Missé Dorothée auteur aut IRD text journalArticle eng text/pdf born digital access Arboviruses such as Dengue, Chikungunya, and Zika viruses represent a major public health problem due to globalization and propagation of susceptible vectors worldwide. Arthropod vector-derived salivary factors have the capacity to modulate human cells function by enhancing or suppressing viral replication and, therefore, modify the establishment of local and systemic viral infection. Here, we discuss how mosquito saliva may interfere with Dengue virus (DENV) infection in humans. Identification of saliva factors that enhance infectivity will allow the production of vector-based vaccines and therapeutics that would interfere with viral transmission by targeting arthropod saliva components. Understanding the role of salivary proteins in DENV transmission will provide tools to control not only Dengue but also other arboviral diseases transmitted by the same vectors. specialized 052 21 139-145 2016 1879-6257 https://www.documentation.ird.fr/hor/fdi:010068797 10.1016/j.coviro.2016.10.001 1879-6257 [F B010068797] https://www.documentation.ird.fr/hor/fdi:010068797 https://www.documentation.ird.fr/intranet/publi/2017/01/010068797.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2017-02-06 2022-03-18 fdi:010068797 fre