@article{fdi:010068797, title = {{T}he effects of mosquito saliva on dengue virus infectivity in humans}, author = {{W}ichit, {S}. and {F}erraris, {P}auline and {C}houmet, {V}. and {M}iss{\'e}, {D}oroth{\'e}e}, editor = {}, language = {{ENG}}, abstract = {{A}rboviruses such as {D}engue, {C}hikungunya, and {Z}ika viruses represent a major public health problem due to globalization and propagation of susceptible vectors worldwide. {A}rthropod vector-derived salivary factors have the capacity to modulate human cells function by enhancing or suppressing viral replication and, therefore, modify the establishment of local and systemic viral infection. {H}ere, we discuss how mosquito saliva may interfere with {D}engue virus ({DENV}) infection in humans. {I}dentification of saliva factors that enhance infectivity will allow the production of vector-based vaccines and therapeutics that would interfere with viral transmission by targeting arthropod saliva components. {U}nderstanding the role of salivary proteins in {DENV} transmission will provide tools to control not only {D}engue but also other arboviral diseases transmitted by the same vectors.}, keywords = {}, booktitle = {}, journal = {{C}urrent {O}pinion in {V}irology}, volume = {21}, numero = {}, pages = {139--145}, ISSN = {1879-6257}, year = {2016}, DOI = {10.1016/j.coviro.2016.10.001}, URL = {https://www.documentation.ird.fr/hor/fdi:010068797}, }