Vantaux Amélie auteur aut IRD Lefèvre Thierry auteur aut IRD Cohuet Anna auteur aut IRD Dabire K. R. auteur aut IRD Roche Benjamin auteur aut IRD Roux Olivier auteur aut IRD text journalArticle eng text/pdf reformatted digital access Exposure to stress during an insect's larval development can have carry-over effects on adult life history traits and susceptibility to pathogens. We investigated the effects of larval nutritional stress for the first time using field mosquito vectors and malaria parasites. In contrast to previous studies, we show that larval nutritional stress may affect human to mosquito transmission antagonistically: nutritionally deprived larvae showed lower parasite prevalence for only one gametocyte carrier; they also had lower fecundity. However, they had greater survival rates that were even higher when infected. When combining these opposing effects into epidemiological models, we show that larval nutritional stress induced a decrease in malaria transmission at low mosquito densities and an increase in transmission at high mosquito densities, whereas transmission by mosquitoes from well-fed larvae was stable. Our work underscores the importance of including environmental stressors towards understanding host-parasite dynamics to improve disease transmission models and control. specialized BURKINA FASO 052 6 art. 36778 [10 p.] 2016 2045-2322 https://www.documentation.ird.fr/hor/fdi:010068363 10.1038/srep36778 2045-2322 [F B010068363] https://www.documentation.ird.fr/hor/fdi:010068363 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers16-12/010068363.pdf IRD - Base Horizon / Pleins textes 2017-01-09 2017-08-23 fdi:010068363 fre