@article{fdi:010068135,
  title = {{F}etal growth restriction is associated with malaria in pregnancy : a prospective longitudinal study in {B}enin},
  author = {{B}riand, {V}al{\'e}rie and {S}aal, {J}. and {G}hafari, {C}. and {H}uynh, {B}. {T}. and {F}ievet, {N}adine and {S}chmiegelow, {C}. and {M}assougbodji, {A}. and {D}eloron, {P}hilippe and {Z}eitlin, {J}. and {C}ot, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground. {F}ew studies have evaluated the effect of malaria on intrauterine growth restriction on the basis of the fetal growth rate, rather than just the small-for-gestational age z score. {H}ere, we assessed the impact of malaria on {IUGR}, using data from a longitudinal, ultrasonography-based follow-up study of {B}eninese women. {M}ethods. {A} total of 1016 women were followed up from gestational week 17 to delivery. {M}alaria was detected every month. {W}omen underwent ultrasonography 4 times for gestational age determination and fetal biometry. {W}e assessed the effect of malaria on birth weight-for-gestational age z score (n = 735 women) and fetal growth velocity (n = 664), defined as a change in fetal weight z score over time. {R}esults. {M}alaria was detected in 43% of women. {F}etal growth velocity was negative overall, decreasing further at the end of the third trimester. {W}omen with >= 2 malarial parasite infections tended to have lower z scores than uninfected women. {M}alaria both in early and late pregnancy was associated with a reduction in fetal growth velocity, which occurred either immediately or with a delay after infection. {D}iscussions. {W}e confirmed the deleterious effect of malaria during both early and late pregnancy on fetal growth. {T}his stresses the importance of starting preventive measures against malaria as early as possible during pregnancy.},
  keywords = {malaria ; pregnancy ; {A}frica ; epidemiology ; fetal growth restriction ; {BENIN}},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {214},
  numero = {3},
  pages = {417--425},
  ISSN = {0022-1899},
  year = {2016},
  DOI = {10.1093/infdis/jiw158},
  URL = {https://www.documentation.ird.fr/hor/fdi:010068135},
}