@article{fdi:010067735, title = {{A} 13-year retrospective study on primary liver cancer in {C}ambodia : a strikingly high hepatitis {C} occurrence among hepatocellular carcinoma cases}, author = {{C}hassagne, {F}. and {R}ojas, {T}. {R}. and {B}ertani, {S}t{\'e}phane and {B}ourdy, {G}enevi{\`e}ve and {E}av, {S}. and {R}uiz, {E}. and {P}ineau, {P}. and {D}eharo, {E}ric}, editor = {}, language = {{ENG}}, abstract = {{O}bjectives: {H}epatocellular carcinoma ({HCC}) is the main type of primary liver cancer ({PLC}) worldwide, but cholangio-carcinoma ({CCA}) may be predominant in some specific regions of {S}outheast {A}sia. {T}he aim of the present study was to delineate a pattern of {C}ambodian {PLC} patients attending the {C}almette {H}ospital in the {C}ambodian capital {P}hnom {P}enh. {M}aterials and {M}ethods: {A} total of 553 medical charts diagnosing {PLC}s from {J}anuary 2003 to {M}ay 2015 were obtained from both the {O}ncology and {H}epato-{G}astroenterology {D}epartments of the {C}almette {H}ospital. {R}esults: {HCC} was the predominant type of {PLC} recorded, with 511 cases (92.4%), whereas {CCA} represented merely 7.6% (42 cases) of the overall series. {H}epatitis {B} virus ({HBV}; 44.3%) and hepatitis {C} virus ({HCV}; 43%) infection rates were similar among the {HCC} patients, while small subsets of {CCA} patients were infected with {HBV} (15.4%) or {HCV} (11.5%). {M}ost {HCC} (84%) and {CCA} (73.8%) patients received palliative treatment only. {C}onclusion: {T}he present study indicates that {HCC} is the main form of primary hepatic neoplasm among {PLC} patients attending a hospital in {C}ambodia. {HBV} and {HCV} infections represented equivalent burdens and major contributing factors to {HCC}. {T}herefore, the implementation of prevention programs for these infectious agents should become a priority for health policy makers in the country.}, keywords = {{H}epatocellular carcinoma ; {C}holangiocarcinoma ; {H}epatitis {B} virus ; {H}epatitis {C} virus ; {O}pisthorchis viverrini ; {C}ambodia ; {CAMBODGE}}, booktitle = {}, journal = {{O}ncology}, volume = {91}, numero = {2}, pages = {106--116}, ISSN = {0030-2414}, year = {2016}, DOI = {10.1159/000446398}, URL = {https://www.documentation.ird.fr/hor/fdi:010067735}, }