Ujvari B. auteur aut IRD Beckmann C. auteur aut IRD Biro P. A. auteur aut IRD Arnal A. auteur aut IRD Tasiemski A. auteur aut IRD Massol F. auteur aut IRD Salzet M. auteur aut IRD Mery F. auteur aut IRD Boidin-Wichlacz C. auteur aut IRD Missé Dorothée auteur aut IRD Renaud F. auteur aut IRD Vittecoq M. auteur aut IRD Tissot T. auteur aut IRD Roche Benjamin auteur aut IRD Poulin R. auteur aut IRD Thomas F. auteur aut IRD text journalArticle eng text/pdf born digital access Despite important differences between infectious diseases and cancers, tumour development (neoplasia) can nonetheless be closely compared to infectious disease because of the similarity of their effects on the body. On this basis, we predict that many of the life-history (LH) responses observed in the context of host-parasite interactions should also be relevant in the context of cancer. Parasites are thought to affect LH traits of their hosts because of strong selective pressures like direct and indirect mortality effects favouring, for example, early maturation and reproduction. Cancer can similarly also affect LH traits by imposing direct costs and/or indirectly by triggering plastic adjustments and evolutionary responses. Here, we discuss how and why a LH focus is a potentially productive but under-exploited research direction for cancer research, by focusing our attention on similarities between infectious disease and cancer with respect to their effects on LH traits and their evolution. We raise the possibility that LH adjustments can occur in response to cancer via maternal/paternal effects and that these changes can be heritable to (adaptively) modify the LH traits of their offspring. We conclude that LH adjustments can potentially influence the transgenerational persistence of inherited oncogenic mutations in populations. specialized Cancer evolutionary ecology life-history traits parasites plasticity 052 080 020 143 5 533-541 2016 0031-1820 https://www.documentation.ird.fr/hor/fdi:010066773 10.1017/s0031182016000147 0031-1820 [F B010066773] https://www.documentation.ird.fr/hor/fdi:010066773 https://www.documentation.ird.fr/intranet/publi/2016/05/010066773.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2016-06-02 2017-08-23 fdi:010066773 fre