@article{fdi:010066741,
  title = {{B}iological status and dietary intakes ofi{I}ron, zinc and vitamin {A} among women and preschool children in rural {B}urkina {F}aso},
  author = {{M}artin-{P}r{\'e}vel, {Y}ves and {A}llemand, {P}auline and {N}ikiema, {L}. and {A}yassou, {K}. {A}. and {O}uedraogo, {H}. {G}. and {M}oursi, {M}. and {D}e {M}oura, {F}. {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {F}ood-based approaches such as biofortification are meant to sustainably address micronutrient deficiencies in poor settings. {K}nowing more about micronutrient intakes and deficiencies is a prerequisite to designing and evaluating interventions. {O}bjective {T}he objectives of the study were to assess biological status and dietary intakes of iron, zinc and vitamin {A} among women and children aged 36-59 months in rural {B}urkina {F}aso and to study relationships between intake and status to better inform future food-based interventions. {D}esign {A} cross-sectional survey was carried out in two rural provinces of {B}urkina {F}aso on a random cluster sample of 480 mother-child pairs. {D}ietary data was obtained by 24-hour recalls repeated on a random sub-selection of 37.5% of subjects to allow calculation of nutrient's probability of adequacy ({PA}). {B}iomarkers were measured on a sub-sample of 180 mother-child pairs. {B}lood samples were analyzed for hemoglobin, serum ferritin, soluble transferrin receptors (s{T}f{R}), {C}-reactive protein, alpha-1-glycoprotein, serum zinc concentration ({SZ}n{C}) and retinol. {F}or each micronutrient the relationship between biomarker and dietary intake was investigated by multiple linear regression models accounting for inflammatory biomarkers. {R}esults {M}ean {PA} for iron, zinc and vitamin {A} was 0.49, 0.87 and 0.21 among women and 0.61, 0.95 and 0.33 among children, respectively. {P}revalence of anemia, corrected low serum ferritin and high s{T}f{R} was 37.6%, 4.0% and 77.5% among women and 72.1%, 1.5% and 87.6% among children, respectively. {P}revalence of low {SZ}n{C} and corrected low serum retinol was 39.4% and 12.0% among women and 63.7% and 24.8% among children, respectively. {T}here was a tendency for a positive relationship between vitamin {A} intakes and serum retinol among women (beta = 0.0003, {P} = 0.06). {O}therwise, no link was found between micronutrients biomarkers and intakes. {C}onclusion {O}ur study depicted different images of micronutrient deficiencies when based on dietary intakes or biomarkers results, thus highlighting the need for more suitable biomarkers and more precise measures of absorbable micronutrient intakes at the individual level. {I}t thus points to challenges in the design and evaluation of future biofortification or other food-based interventions in rural areas of {B}urkina {F}aso.},
  keywords = {{BURKINA} {FASO}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {11},
  numero = {3},
  pages = {e0146810 [17 p.]},
  ISSN = {1932-6203},
  year = {2016},
  DOI = {10.1371/journal.pone.0146810},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066741},
}