Loeuillet C. auteur aut IRD Banuls Anne-Laure auteur aut IRD Hide M. auteur aut IRD text journalArticle eng text/pdf reformatted digital access Although leishmaniases are endemic in 98 countries, they are still considered neglected tropical diseases. Leishmaniases are characterized by the emergence of new virulent and asymptomatic strains of Leishmania spp. and, as a consequence, by a very diverse clinical spectrum. To fight more efficiently these parasites, the mechanisms of host defense and of parasite virulence need to be thoroughly investigated. To this aim, animal models are widely used. However, the results obtained with these models are influenced by several experimental parameters, such as the mouse genetic background, parasite genotype, inoculation route/infection site, parasite dose and phlebotome saliva. In this review, we propose an update on their influence in the two main clinical forms of the disease: cutaneous and visceral leishmaniases. specialized Leishmaniases Visceral Cutaneous Mice Dose Inoculation site Saliva 052 080 9 art. 144 [12 p.] 2016 1756-3305 https://www.documentation.ird.fr/hor/fdi:010066665 10.1186/s13071-016-1413-9 1756-3305 [F B010066665] https://www.documentation.ird.fr/hor/fdi:010066665 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers16-04/010066665.pdf IRD - Base Horizon / Pleins textes 2016-05-03 2018-12-17 fdi:010066665 fre