Berthier D. auteur aut IRD Brenière Simone Frédérique auteur aut IRD Bras Goncalves Rachel auteur aut IRD Lemesre Jean-Loup auteur aut IRD Jamonneau Vincent auteur aut IRD Solano Philippe auteur aut IRD Lejon Veerle auteur aut IRD Thévenon S. auteur aut IRD Bucheton Bruno auteur aut IRD text journalArticle eng text/pdf born digital access So far, research on trypanosomatid infections has been driven by 'disease by disease' approaches, leading to different concepts and control strategies. It is, however, increasingly clear that they share common features such as the ability to generate long-lasting asymptomatic infections in their mammalian hosts. Trypanotolerance, long integrated in animal African trypanosomiasis control, historically refers to the ability of cattle breeds to limit Trypanosoma infection and pathology, but has only recently been recognized in humans. Whilst trypanotolerance is absent from the vocabulary on leishmaniasis and Chagas disease, asymptomatic infections also occur. We review the concept of trypanotolerance across the trypanosomatids and discuss the importance of asymptomatic carriage in the current context of elimination. specialized MONDE 052 32 2 157-168 2016 1471-4922 https://www.documentation.ird.fr/hor/fdi:010066469 10.1016/j.pt.2015.11.001 1471-4922 [F B010066469] https://www.documentation.ird.fr/hor/fdi:010066469 https://www.documentation.ird.fr/intranet/publi/depot/2016-03-04/010066469.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2016-03-04 2016-07-12 fdi:010066469 fre