@article{fdi:010066469, title = {{T}olerance to trypanosomatids : a threat, or a key for disease elimination ?}, author = {{B}erthier, {D}. and {B}reni{\`e}re, {S}imone {F}r{\'e}d{\'e}rique and {B}ras {G}oncalves, {R}achel and {L}emesre, {J}ean-{L}oup and {J}amonneau, {V}incent and {S}olano, {P}hilippe and {L}ejon, {V}eerle and {T}h{\'e}venon, {S}. and {B}ucheton, {B}runo}, editor = {}, language = {{ENG}}, abstract = {{S}o far, research on trypanosomatid infections has been driven by 'disease by disease' approaches, leading to different concepts and control strategies. {I}t is, however, increasingly clear that they share common features such as the ability to generate long-lasting asymptomatic infections in their mammalian hosts. {T}rypanotolerance, long integrated in animal {A}frican trypanosomiasis control, historically refers to the ability of cattle breeds to limit {T}rypanosoma infection and pathology, but has only recently been recognized in humans. {W}hilst trypanotolerance is absent from the vocabulary on leishmaniasis and {C}hagas disease, asymptomatic infections also occur. {W}e review the concept of trypanotolerance across the trypanosomatids and discuss the importance of asymptomatic carriage in the current context of elimination.}, keywords = {{MONDE}}, booktitle = {}, journal = {{T}rends in {P}arasitology}, volume = {32}, numero = {2}, pages = {157--168}, ISSN = {1471-4922}, year = {2016}, DOI = {10.1016/j.pt.2015.11.001}, URL = {https://www.documentation.ird.fr/hor/fdi:010066469}, }