@article{fdi:010066045,
  title = {{A}cute febrile illness and influenza disease burden in a rural cohort dedicated to malaria in {S}enegal, 2012-2013},
  author = {{S}arr, {F}. {D}. and {N}iang, {M}. and {T}hiam, {D}. and {D}ia, {N}. and {B}adiane, {A}. and {N}dao, {A}. {B}. and {S}okhna, {C}heikh and {S}piegel, {A}. and {R}ichard, {V}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {A}frican populations are considered to be particularly vulnerable to fever illnesses, including malaria, and acute respiratory disease, owing to limited resources and overcrowding. {H}owever, the overall burden of influenza in this context is poorly defined and incidence data for {A}frican countries are scarce. {W}e therefore studied the fever syndrome incidence and more specifically influenza incidence in a cohort of inhabitants of {D}ielmo and {N}diop in {S}okone district, {S}enegal. {M}ethods {D}aily febrile-illness data were prospectively obtained from {J}anuary 2012 to {D}ecember 2013 from the cohort of the villages of {D}ielmo and {N}diop, initially dedicated to the study of malaria. {N}asopharyngeal swabs were collected from, and malaria diagnosis tests (thick blood smears) carried out on, every febrile individual during clinical visits; reverse transcriptase- polymerase chain reaction was used to identify influenza viruses in the samples. {B}inomial negative regression analysis was used to study the relationship between the monthly incidence rate and various covariates. {R}esults {I}n {D}ielmo and {N}diop, the incidence ofmalaria has decreased, but fever syndromes remain frequent. {A}mong the 1036 inhabitants included in the cohort, a total of 1,129 episodes of fever were reported. {I}nfluenza was present all year round with peaks in {O}ctober-{D}ecember 2012 and {A}ugust 2013. {T}he fever, {ILI} and influenza incidence density rates differed significantly between age groups. {A}t both sites, the adjusted incidence relative risks for fever syndromes and {ILI} were significantly higher in the [6-24 months) than other age groups: 7.3 (95% {CI}: [5.7-9.3]) and 16.1 (95% {CI}: [11.1-23.3]) respectively. {T}he adjusted incidence relative risk for influenza was significantly higher for the [0-6 months) than other age groups: 9.9 (95% {CI}: [2.9-33.6]). {A}t both sites, incidence density rates were lowest among adults > = 50 years. {C}onclusions {I}n this rural setting in {S}enegal, influenza was most frequent among the youngest children. {P}reventive strategies targeting this population should be implemented.},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {10},
  numero = {12},
  pages = {e0143999 [12 p.]},
  ISSN = {1932-6203},
  year = {2015},
  DOI = {10.1371/journal.pone.0143999},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066045},
}