@article{fdi:010065536,
  title = {{C}onvergent evolution of endosymbiont differentiation in dalbergioid and inverted repeat-lacking clade legumes mediated by nodule-specific cysteine-rich peptides},
  author = {{C}zernic, {P}. and {G}ully, {D}jamel and {C}artieaux, {F}abienne and {M}oulin, {L}ionel and {G}uefrachi, {I}. and {P}atrel, {D}elphine and {P}ierre, {O}. and {F}ardoux, {J}o{\¨e}l and {C}haintreuil, {C}l{\'e}mence and {N}guyen, {P}. and {G}ressent, {F}. and {D}a {S}ilva, {C}. and {P}oulain, {J}. and {W}incker, {P}. and {R}ofidal, {V}. and {H}em, {S}. and {B}arri{\`e}re, {Q}. and {A}rrighi, {J}ean-{F}ran{\c{c}}ois and {M}ergaert, {P}. and {G}iraud, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{N}utritional symbiotic interactions require the housing of large numbers of microbial symbionts, which produce essential compounds for the growth of the host. {I}n the legume-rhizobium nitrogen-fixing symbiosis, thousands of rhizobium microsymbionts, called bacteroids, are confined intracellularly within highly specialized symbiotic host cells. {I}n {I}nverted {R}epeat-{L}acking {C}lade ({IRLC}) legumes such as {M}edicago spp., the bacteroids are kept under control by an arsenal of nodule-specific cysteine-rich ({NCR}) peptides, which induce the bacteria in an irreversible, strongly elongated, and polyploid state. {H}ere, we show that in {A}eschynomene spp. legumes belonging to the more ancient {D}albergioid lineage, bacteroids are elongated or spherical depending on the {A}eschynomene spp. and that these bacteroids are terminally differentiated and polyploid, similar to bacteroids in {IRLC} legumes. {T}ranscriptome, in situ hybridization, and proteome analyses demonstrated that the symbiotic cells in the {A}eschynomene spp. nodules produce a large diversity of {NCR}-like peptides, which are transported to the bacteroids. {B}locking {NCR} transport by {RNA} interference-mediated inactivation of the secretory pathway inhibits bacteroid differentiation. {T}ogether, our results support the view that bacteroid differentiation in the {D}albergioid clade, which likely evolved independently from the bacteroid differentiation in the {IRLC} clade, is based on very similar mechanisms used by {IRLC} legumes.},
  keywords = {},
  booktitle = {},
  journal = {{P}lant {P}hysiology},
  volume = {169},
  numero = {2},
  pages = {1254--1265},
  ISSN = {0032-0889},
  year = {2015},
  DOI = {10.1104/pp.15.00584},
  URL = {https://www.documentation.ird.fr/hor/fdi:010065536},
}