Hoa L. N. M. auteur aut IRD Bryant J. E. auteur aut IRD Choisy Marc auteur aut IRD Nguyet L. A. auteur aut IRD Bao N. T. auteur aut IRD Trang N. H. auteur aut IRD Chuc N. T. K. auteur aut IRD Toan T. K. auteur aut IRD Saito T. auteur aut IRD Takemae N. auteur aut IRD Horby P. auteur aut IRD Wertheim H. auteur aut IRD Fox A. auteur aut IRD text journalArticle eng text/pdf born digital access A reassortant swine-origin A(H3N2) virus (A/swine/BinhDuong/03-9/2010) was detected through swine surveillance programmes in southern Vietnam in 2010. This virus contains haemagglutinin and neuraminidase genes from a human A(H3N2) virus circulating around 2004-2006, and the internal genes from triple-reassortant swine influenza A viruses (IAVs). To assess population susceptibility to this virus we measured haemagglutination inhibiting (HI) titres to A/swine/BinhDuong/03-9/2010 and to seasonal A/Perth/16/2009 for 947 sera collected from urban and rural Vietnamese people during 2011-2012. Seroprevalence (HI >= 40) was high and similar for both viruses, with 62.6% [95% confidence interval (CI) 59.4-65.7] against A/Perth/16/2009 and 54.6% (95% CI 51.4-57.8%) against A/swine/BinhDuong/03-9/2010, and no significant differences between urban and rural participants. Children aged <5 years lacked antibodies to the swine origin H3 virus despite high seroprevalence for A/Perth/16/2009. These results reveal vulnerability to infection to this contemporary swine IAV in children aged <5 years; however, cross-reactive immunity in adults would likely limit epidemic emergence potential. specialized Influenza A virology (human) and epidemiology zoonoses VIET NAM 052 143 14 2959-2964 2015 0950-2688 https://www.documentation.ird.fr/hor/fdi:010065387 10.1017/s0950268815000187 0950-2688 [F B010065387] https://www.documentation.ird.fr/hor/fdi:010065387 https://www.documentation.ird.fr/intranet/publi/2015/11/010065387.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2015-12-04 2017-08-23 fdi:010065387 fre