Bassene H. auteur aut IRD Sambou M. auteur aut IRD Fenollar F. auteur aut IRD Clarke S. auteur aut IRD Djiba S. auteur aut IRD Mourembou G. auteur aut IRD Badara L. Y. A. auteur aut IRD Raoult D. auteur aut IRD Mediannikov Oleg auteur aut IRD text journalArticle eng text/pdf reformatted digital access Large parts of African and American countries are colonized by Mansonella, a very common but poorly described filarial nematode. Bloodsucking flies of the genus Culicoides are suspected to be the vector of Mansonella perstans, but no study in Senegal has confirmed that Culicoides can transmit the parasite. Designed specific real-time quantitative polymerase chain reaction (qPCR) can be used to identify microfilaria in stained blood smears. This study was performed in July and December 2010 in the southeastern Senegal, which is known to be endemic for M. perstans. We analyzed 297 blood smears from febrile and afebrile resident people by qPCR. The global prevalence of M. perstans was approximately 14.5% in both febrile and afebrile individuals. The age group of > 30 years had the highest prevalence (22.0%). No Culicoides among 1,159 studied specimens was positive for M. perstans and its vector in Senegal still requires identification. specialized SENEGAL 052 93 3 601-606 2015 0002-9637 https://www.documentation.ird.fr/hor/fdi:010065287 10.4269/ajtmh.15-0051 0002-9637 [F B010065287] https://www.documentation.ird.fr/hor/fdi:010065287 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010065287.pdf IRD - Base Horizon / Pleins textes 2015-11-06 2025-06-13 fdi:010065287 fre