@article{fdi:010064907,
  title = {{B}lood-brain barrier function and biomarkers of central nervous system injury in {R}ickettsial versus other neurological infections in {L}aos},
  author = {{D}ittrich, {S}. and {S}unyakumthorn, {P}. and {R}attanavong, {S}. and {P}hetsouvanh, {R}. and {P}anyanivong, {P}. and {S}engduangphachanh, {A}. and {P}houminh, {P}. and {A}nantatat, {T}. and {C}hanthongthip, {A}. and {L}ee, {S}. {J}. and {D}ubot {P}{\'e}r{\`e}s, {A}udrey and {D}ay, {N}. {P}. {J}. and {P}aris, {D}. {H}. and {N}ewton, {P}. {N}. and {T}urner, {G}. {D}. {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}lood-brain barrier ({BBB}) function and cerebrospinal fluid ({CSF}) biomarkers were measured in patients admitted to hospital with severe neurological infections in the {L}ao {P}eople's {D}emocratic {R}epublic ({N} = 66), including bacterial meningitis ({BM}; {N} = 9) or tuberculosis meningitis ({TBM}; {N} = 11), {J}apanese encephalitis virus ({JEV}; {N} = 25), and rickettsial infections ({N} = 21) including murine and scrub typhus patients. {T}he albumin index ({A}l) and glial fibrillary acidic protein ({GFAP}) levels were significantly higher in {BM} and {TBM} than other diseases but were also raised in individual rickettsial patients. {T}otal tau protein was significantly raised in the {CSF} of {JEV} patients. {N}o differences were found between clinical or neurological symptoms, {A}l, or biomarker levels that allowed distinction between severe neurological involvement by {O}rientia tsutsugamushi compared with {R}ickettsia species.},
  keywords = {{LAOS}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {93},
  numero = {2},
  pages = {232--237},
  ISSN = {0002-9637},
  year = {2015},
  DOI = {10.4269/ajtmh.15-0119},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064907},
}