Hutin M. auteur aut IRD Perez-Quintero A. L. auteur aut IRD Lopez C. auteur aut IRD Szurek Boris auteur aut IRD text journalArticle eng text/pdf born digital access Many plant-pathogenic xanthomonads rely on Transcription Activator-Like (TAL) effectors to colonize their host. This particular family of type Ill effectors functions as specific plant transcription factors via a programmable DNA-binding domain. Upon binding to the promoters of plant disease susceptibility genes in a sequence-specific manner, the expression of these host genes is induced. However, plants have evolved specific strategies to counter the action of TAL effectors and confer resistance. One mechanism is to avoid the binding of TAL effectors by mutations of their DNA binding sites, resulting in resistance by loss-of-susceptibility. This article reviews our current knowledge of the susceptibility hubs targeted by Xanthomonas TAL effectors, possible evolutionary scenarios for plants to combat the pathogen with loss-of-function alleles, and how this knowledge can be used overall to develop new pathogen-informed breeding strategies and improve crop resistance. specialized Xanthomonas plant disease susceptibility S genes hubs TAL effectors agricultural biotechnology loss-of-function alleles 076 084 6 art. 535 [12 ] [+ Corrigendum art. 647 [1 p.]] 2015 1664-462X https://www.documentation.ird.fr/hor/fdi:010064872 10.3389/fpls.2015.00535 1664-462X [F B010064872] https://www.documentation.ird.fr/hor/fdi:010064872 https://www.documentation.ird.fr/intranet/publi/depot/2015-10-08/010064872.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2015-09-04 2026-07-21 fdi:010064872 fre