@article{fdi:010064639,
  title = {{T}he implication of long-lasting insecticide-treated net use in the resurgence of malaria morbidity in a {S}enegal malaria endemic village in 2010-2011},
  author = {{W}otodjo, {A}. {N}. and {R}ichard, {V}. and {B}oyer, {S}. and {D}oucour{\'e}, {S}. and {D}iagne, {N}. and {T}oure-{B}alde, {A}. and {T}all, {A}. and {F}aye, {N}. and {G}audart, {J}. and {T}rape, {J}ean-{F}ran{\c{c}}ois and {S}okhna, {C}heikh},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {A}lthough the burden of malaria has significantly declined in recent years in sub-{S}aharan {A}frica through the widespread use of long-lasting insecticide treated bed-nets ({LLIN}s) and artemisinin-based combination therapy, resurgence of malaria is observed in some settings after several years of {LLIN}s use. {T}his study aimed to assess if {LLIN}s use remains protective against malaria during a period of resurgence of malaria morbidity in {D}ielmo, a rural village of {S}enegal. {M}ethods: {I}n {J}uly 2008, {LLIN}s were offered to all villagers and lately in {J}uly 2011, {LLIN}s were renewed. {A} longitudinal study was conducted between {J}uly, 2010 and {D}ecember, 2011 among inhabitants of the village of {D}ielmo to identify all episodes of fever. {T}hick smears stained with {G}iemsa were done for every febrile villager and malaria attacks were treated with combination of {A}rtesunate plus {A}modiaquine. {C}ross-sectional surveys were also conducted at the end of the rainy season ({O}ctober 2010 and {N}ovember 2011) to assess asymptomatic carriage. {A} survey on {LLIN}s use was done every quarter of the year. {A} random-effect logistic regression was used to assess the effect of {LLIN}s use on the risk of having a malaria attack after adjusting for the main risk factors. {R}esults: {T}he study population included 449 individuals corresponding to a total of 2140 observations. {O}ne hundred and fifteen (115) clinical malaria attacks attributed to {P}. falciparum (cases) have been recorded over the study period. {M}ost of the malaria cases occurred in {O}ctober-{D}ecember 2010 (49/115 i.e. 43%) and among adults aged 15 years and over (50/115, i.e. 43%). {D}uring the study period, the use of {LLIN}s was 61% among non-malaria cases and only 42% among malaria clinical cases but differenced according to age group. {A}fter adjusting on gender, age, rainfall and {LLIN}s replacement, we found that {LLIN}s use ({AOR} [95%{CI}] = 0.40 [0.25; 0.62], p < 0.001) remained a protective factor against malaria attacks during the study period. {C}onclusion: {LLIN}s use remains effective to reduce malaria burden. {T}hese results highlight the need to pursue {LLIN}s implementation in the current context of malaria elimination and to provide positive incentives to increase its use in the population.},
  keywords = {{M}alaria ; {R}esurgence ; {L}ong-lasting insecticide treated bed-nets ; {DIELMO} ; {S}enegal ; {SENEGAL}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {8},
  numero = {},
  pages = {267},
  ISSN = {1756-3305},
  year = {2015},
  DOI = {10.1186/s13071-015-0871-9},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064639},
}