@article{fdi:010064123, title = {{E}bola and {M}arburg haemorrhagic fever}, author = {{R}ougeron, {V}. and {F}eldmann, {H}. and {G}rard, {G}. and {B}ecker, {S}. and {L}eroy, {E}ric}, editor = {}, language = {{ENG}}, abstract = {{E}bolaviruses and {M}arburgviruses (family {F}iloviridae) are among the most virulent pathogens for humans and great apes causing severe haemorrhagic fever and death within a matter of days. {T}his group of viruses is characterized by a linear, non-segmented, single-stranded {RNA} genome of negative polarity. {T}he overall burden of filovirus infections is minimal and negligible compared to the devastation caused by malnutrition and other infectious diseases prevalent in {A}frica such as malaria, dengue or tuberculosis. {I}n this paper, we review the knowledge gained on the eco/epidemiology, the pathogenesis and the disease control measures for {M}arburg and {E}bola viruses developed over the last 15 years. {T}he overall progress is promising given the little attention that these pathogen have achieved in the past; however, more is to come over the next decade given the more recent interest in these pathogens as potential public and animal health concerns. {L}icensing of therapeutic and prophylactic options may be achievable over the next 5-10 years.}, keywords = {{AFRIQUE}, {GABON}, {OUGANDA}, {CONGO} ; {NIGERIA} ; {COTE} {D}'{IVOIRE} ; {GUINEE} ; {SIERRA} {LEONE} ; {LIBERIA} ; {ANGOLA} ; {AFRIQUE} {DU} {SUD} ; {SOUDAN} ; {KENYA} ; {REPUBLIQUE} {DEMOCRATIQUE} {DU} {CONGO} ; {ASIE} ; {PHILIPPINES} ; {EUROPE} ; {ESPAGNE}}, booktitle = {}, journal = {{J}ournal of {C}linical {V}irology}, volume = {64}, numero = {}, pages = {111--119}, ISSN = {1386-6532}, year = {2015}, DOI = {10.1016/j.jcv.2015.01.014}, URL = {https://www.documentation.ird.fr/hor/fdi:010064123}, }