%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Gaye, A.
%A Bousema, T.
%A Libasse, G.
%A Ndiath, M. O.
%A Konate, L.
%A Jawara, M.
%A Faye, O.
%A Sokhna, Cheikh
%T Infectiousness of the human population to Anopheles arabiensis by direct skin feeding in an area hypoendemic for malaria in Senegal
%D 2015
%L fdi:010064001
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%K SENEGAL
%M ISI:000350529400039
%N 3
%P 648-652
%R 10.4269/ajtmh.14-0402
%U https://www.documentation.ird.fr/hor/fdi:010064001
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010064001.pdf
%V 92
%W Horizon (IRD)
%X Direct skin feeding experiments are sensitive assays to determine human infectiousness to mosquitoes but are rarely used in malaria epidemiological surveys. We determined the infectiousness of inhabitants of a malaria hypoendemic area in Senegal. Gametocyte prevalence by microscopy was 13.5% (26 of 192). Of all individuals who were gametocyte positive, 44.4% (11 of 25) infected >= 1 Anopheles arabiensis mosquito and 10.8% (54 of 500) of mosquitoes became infected. Of all individuals who were gametocyte negative by microscopy, 4.3% (7 of 162) infected 1 mosquito and 0.4% (12 of 3240) of mosquitoes became infected. The 18.2% (12 of 66) of all mosquito infections was a result of submicroscopic gametocyte carriage and two individuals without asexual parasites or gametocytes by microscopy were infectious to mosquitoes. When infectivity and local demography was taken into account, children 5-14 years of age contributed 50.8% of the human infectious reservoir for malaria. Adults and submicroscopic gametocyte carriers may contribute considerably to onward malaria transmission in our setting.
%$ 052