@article{fdi:010063987,
  title = {{A}ddressing social issues in a universal {HIV} test and treat intervention trial ({ANRS} 12249 {T}as{P}) in {S}outh {A}frica : methods for appraisal},
  author = {{O}rne-{G}liemann, {J}. and {L}armarange, {J}oseph and {B}oyer, {S}. and {I}wuji, {C}. and {M}c{G}rath, {N}. and {B}arnighausen, {T}. and {Z}uma, {T}. and {D}ray-{S}pira, {R}. and {S}pire, {B}. and {R}ochat, {T}. and {L}ert, {F}. and {I}mrie, {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he {U}niversal {HIV} {T}est and {T}reat ({UTT}) strategy represents a challenge for science, but is also a challenge for individuals and societies. {A}re repeated offers of provider-initiated {HIV} testing and immediate antiretroviral therapy ({ART}) socially-acceptable and can these become normalized over time? {C}an {UTT} be implemented without potentially adding to individual and community stigma, or threatening individual rights? {W}hat are the social, cultural and economic implications of {UTT} for households and communities? {A}nd can {UTT} be implemented within capacity constraints and other threats to the overall provision of {HIV} services? {T}he answers to these research questions will be critical for routine implementation of {UTT} strategies. {M}ethods/design: {A} social science research programme is nested within the {ANRS} 12249 {T}reatment-as-{P}revention ({T}as{P}) cluster-randomised trial in rural {S}outh {A}frica. {T}he programme aims to inform understanding of the (i) social, economic and environmental factors affecting uptake of services at each step of the continuum of {HIV} prevention, treatment and care and (ii) the causal impacts of the {T}as{P} intervention package on social and economic factors at the individual, household, community and health system level. {W}e describe a multidisciplinary, multi-level, mixed-method research protocol that includes individual, household, community and clinic surveys, and combines quantitative and qualitative methods. {D}iscussion: {T}he {UTT} strategy is changing the overall approach to {HIV} prevention, treatment and care, and substantial social consequences may be anticipated, such as changes in social representations of {HIV} transmission, prevention, {HIV} testing and {ART} use, as well as changes in individual perceptions and behaviours in terms of uptake and frequency of {HIV} testing and {ART} initiation at high {CD}4. {T}riangulation of social science studies within the {ANRS} 12249 {T}as{P} trial will provide comprehensive insights into the acceptability and feasibility of the {T}as{P} intervention package at individual, community, patient and health system level, to complement the trial's clinical and epidemiological outcomes. {I}t will also increase understanding of the causal impacts of {UTT} on social and economic outcomes, which will be critical for the long-term sustainability and routine {UTT} implementation.},
  keywords = {{HIV} infections ; {HIV} testing ; {C}ommunity ; {HIV} care ; {A}ntiretroviral treatment ; {S}ocial ; {B}ehaviour ; {C}ost ; {S}outh {A}frica ; {AFRIQUE} {DU} {SUD}},
  booktitle = {},
  journal = {{B}mc {P}ublic {H}ealth},
  volume = {15},
  numero = {},
  pages = {art. 209 [14 p.]},
  ISSN = {1471-2458},
  year = {2015},
  DOI = {10.1186/s12889-015-1344-y},
  URL = {https://www.documentation.ird.fr/hor/fdi:010063987},
}