@article{fdi:010063154,
  title = {{G}orilla gorilla gorilla gut : a potential reservoir of pathogenic bacteria as revealed using culturomics and molecular tools},
  author = {{B}ittar, {F}. and {K}eita, {M}. {B}. and {L}agier, {J}. {C}. and {P}eeters, {M}artine and {D}elaporte, {E}ric and {R}aoult, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{W}ild apes are considered to be the most serious reservoir and source of zoonoses. {H}owever, little data are available about the gut microbiota and pathogenic bacteria in gorillas. {F}or this propose, a total of 48 fecal samples obtained from 21 {G}orilla gorilla gorilla individuals (as revealed via microsatellite analysis) were screened for human bacterial pathogens using culturomics and molecular techniques. {B}y applying culturomics to one index gorilla and using specific media supplemented by plants, we tested 12,800 colonies and identified 147 different bacterial species, including 5 new species. {M}any opportunistic pathogens were isolated, including 8 frequently associated with human diseases; {M}ycobacterium bolletii, {P}roteus mirabilis, {A}cinetobacter baumannii, {K}lebsiella pneumoniae, {S}erratia marcescens, {E}scherichia coli, {S}taphylococcus aureus and {C}lostridium botulinum. {T}he genus {T}reponema accounted for 27.4% of the total reads identified at the genus level via 454 pyrosequencing. {U}sing specific real-time {PCR} on 48 gorilla fecal samples, in addition to classical human pathogens, we also observed the fastidious bacteria {B}artonella spp. {B}orrelia spp., {C}oxiella burnetii and {T}ropheryma whipplei in the gorilla population. {W}e estimated that the prevalence of these pathogens vary between 4.76% and 85.7%. {T}herefore, gorillas share many bacterial pathogens with humans suggesting that they could be a reservoir for their emergence.},
  keywords = {{CAMEROUN}},
  booktitle = {},
  journal = {{S}cientific {R}eports},
  volume = {4},
  numero = {},
  pages = {art. 7174 [5 p.]},
  ISSN = {2045-2322},
  year = {2014},
  DOI = {10.1038/srep07174},
  URL = {https://www.documentation.ird.fr/hor/fdi:010063154},
}