@article{fdi:010062575,
  title = {{T}he early spread and epidemic ignition of {HIV}-1 in human populations},
  author = {{F}aria, {N}. {R}. and {R}ambaut, {A}. and {S}uchard, {M}. {A}. and {B}aele, {G}. and {B}edford, {T}. and {W}ard, {M}. {J}. and {T}atem, {A}. {J}. and {S}ousa, {J}. {D}. and {A}rinaminpathy, {N}. and {P}epin, {J}. and {P}osada, {D}. and {P}eeters, {M}artine and {P}ybus, {O}. {G}. and {L}emey, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}hirty years after the discovery of {HIV}-1, the early transmission, dissemination, and establishment of the virus in human populations remain unclear. {U}sing statistical approaches applied to {HIV}-1 sequence data from central {A}frica, we show that from the 1920s {K}inshasa (in what is now the {D}emocratic {R}epublic of {C}ongo) was the focus of early transmission and the source of pre-1960 pandemic viruses elsewhere. {L}ocation and dating estimates were validated using the earliest {HIV}-1 archival sample, also from {K}inshasa. {T}he epidemic histories of {HIV}-1 group {M} and nonpandemic group {O} were similar until similar to 1960, after which group {M} underwent an epidemiological transition and outpaced regional population growth. {O}ur results reconstruct the early dynamics of {HIV}-1 and emphasize the role of social changes and transport networks in the establishment of this virus in human populations.},
  keywords = {{AFRIQUE} {CENTRALE} ; {REPUBLIQUE} {DEMOCRATIQUE} {DU} {CONGO}},
  booktitle = {},
  journal = {{S}cience},
  volume = {346},
  numero = {6205},
  pages = {56--61},
  ISSN = {0036-8075},
  year = {2014},
  DOI = {10.1126/science.1256739},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062575},
}