@article{fdi:010062431,
  title = {{F}ull-length genome analyses of two new {S}imian {I}mmunodeficiency {V}irus ({SIV}) strains from mustached monkeys ({C}. cephus) in {G}abon illustrate a complex evolutionary history among the {SIV}mus/mon/gsn lineage},
  author = {{L}i{\'e}geois, {F}lorian and {S}chmidt, {F}. and {B}ou{\'e}, {V}. and {B}utel, {C}hristelle and {M}ouacha, {F}atima and {N}gari, {P}. and {O}ndo, {B}. {M}. and {L}eroy, {E}ric and {H}eeney, {J}. {L}. and {D}elaporte, {E}ric and {P}eeters, {M}artine and {R}ouet, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he {S}imian {I}mmunodeficiency {V}irus ({SIV}) mus/mon/gsn lineage is a descendant of one of the precursor viruses to the {HIV}-1/{SIV}cpz/gor viral lineage. {SIV}mus and {SIV}gsn were sequenced from mustached and greater spot nosed monkeys in {C}ameroon and {SIV}mon from mona monkeys in {C}ameroon and {N}igeria. {I}n order to further document the genetic diversity of {SIV}mus, we analyzed two full-length genomes of new strains identified in {G}abon. {T}he whole genomes obtained showed the expected reading frames for gag, pol, vif, vpr, tat, rev, env, nef, and also for a vpu gene. {A}nalyses showed that the {G}abonese {SIV}mus strains were closely related and formed a monophyletic clade within the {SIV}mus/mon/gsn lineage. {N}onetheless, within this lineage, the position of both new {SIV}mus differed according to the gene analyzed. {I}n pol and nef gene, phylogenetic topologies suggested different evolutions for each of the two new {SIV}mus strains whereas in the other nucleic fragments studied, their positions fluctuated between {SIV}mon, {SIV}mus-1, and {SIV}gsn. {I}n addition, in {C}1 domain of env, we identified an insertion of seven amino acids characteristic for the {SIV}mus/mon/gsn and {HIV}-1/{SIV}cpz/{SIV}gor lineages. {O}ur results show a high genetic diversity of {SIV}mus in mustached monkeys and suggest cross-species transmission events and recombination within {SIV}mus/mon/gsn lineage. {A}dditionally, in {C}entral {A}frica, hunters continue to be exposed to these simian viruses, and this represents a potential threat to humans.},
  keywords = {{SIV} ; lentivirus ; non-human primate ; molecular phylogeny ; evolution ; bushmeat ; cross-species transmission ; {G}abon ; {GABON}},
  booktitle = {},
  journal = {{V}iruses-{B}asel},
  volume = {6},
  numero = {7},
  pages = {2880--2898},
  ISSN = {1999-4915},
  year = {2014},
  DOI = {10.3390/v6072880},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062431},
}