@article{fdi:010062305,
  title = {{I}mmune trypanolysis test with blood spotted on filter paper for epidemiological surveillance of sleeping sickness},
  author = {{C}amara, {O}. and {C}amara, {M}. and {L}ejon, {V}eerle and {I}lboudo, {H}. and {S}akande, {H}. and {L}eno, {M}. and {B}uscher, {P}. and {B}ucheton, {B}runo and {J}amonneau, {V}incent},
  editor = {},
  language = {{ENG}},
  abstract = {{OBJECTIVES} {T}he immune trypanolysis test ({TL}) is an accurate sero-diagnostic tool increasingly implemented for sleeping sickness medical surveillance, but it is restricted to the reference laboratories. {T}o facilitate storage and transport of the test specimen, we developed a protocol for the examination of blood spotted on filter paper ({TL}-fp) that can be stored and shipped at ambient temperature. {W}e compared its performance with the classical {TL} on plasma ({TL}-pl) that needs to be kept frozen until use. {METHODS} {T}he study was conducted in active foci of the {R}epublic of {G}uinea. {I}n total, 438 specimens from treated and untreated sleeping sickness patients and serological suspects were tested with both methods. {RESULT} {TL}-fp gave significantly less positive results than {TL}-pl, but all the confirmed sleeping sickness cases were positive with the {TL}-fp protocol. {CONCLUSION} {TL}-fp appears to offer a good compromise between feasibility and sensitivity to detect currently infected subjects who play a role in the transmission of {T}rypanosoma brucei gambiense and is useful for contributing to the elimination of gambiense sleeping sickness.},
  keywords = {human {A}frican trypanosomiasis ; diagnosis ; immune trypanolysis test ; filter paper ; antibody ; surveillance ; {GUINEE}},
  booktitle = {},
  journal = {{T}ropical {M}edicine and {I}nternational {H}ealth},
  volume = {19},
  numero = {7},
  pages = {828--831},
  ISSN = {1360-2276},
  year = {2014},
  DOI = {10.1111/tmi.12316},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062305},
}