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    <titleInfo>
      <title>Epidemiology of snakebite and use of antivenom in Argentina</title>
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    <name type="personnal">
      <namePart type="family">Dolab</namePart>
      <namePart type="given">J. A.</namePart>
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      <namePart type="family">de Roodt</namePart>
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      <namePart type="family">de Titto</namePart>
      <namePart type="given">E. H.</namePart>
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      <namePart type="family">Salomon</namePart>
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      <namePart type="family">Chippaux</namePart>
      <namePart type="given">Jean-Philippe</namePart>
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    <abstract>Background: The incidence and case fatality rate of snakebite in Argentina are poorly known. Methods: The authors used questionnaires provided with antivenoms by the primary manufacturer of anti-venoms in Argentina. Results: A total of 8083 completed questionnaires was collected between 1978 and 1998. The annual incidence of snakebite was 1.8 bites per 100 000 inhabitants, with a high geographical heterogeneity; in the northern provinces of the country, the incidence can exceed 150 snakebites per 100 000 people per year. Bothrops (pit viper) bites predominated, accounting for 96.6 (6720/6957) of envenomations, bites from Crotalus (rattlesnake) accounted for 2.8 (195/6957), and bites from Micrurus (coral snake) for 0.6 (42/6957). Most patients were young men, who were generally bitten during agricultural activities, i.e. while working in the fields. Most snakebites (78.9, 5852/7419) were to the lower limb, including 58.3 (4322/7419) to the foot. The case fatality rate was 0.04 (3/8083). Most envenomations (90, 7275/8083) were treated with specific antivenom during the first 4 h after the bite. The median dose of antivenom was two vials for viper bites (Bothrops and Crotalus) and three vials for Micrurus bites. Conclusion: These preliminary results should enable manufacturers to increase the availability of appropriate antivenom and health authorities to improve the management of snakebites where they are most common.</abstract>
    <targetAudience authority="marctarget">specialized</targetAudience>
    <subject>
      <topic>Antivenom</topic>
      <topic>Argentina</topic>
      <topic>Bothrops</topic>
      <topic>Crotalus</topic>
      <topic>Micrurus</topic>
      <topic>Snakebite</topic>
    </subject>
    <subject authority="local">
      <geographic>ARGENTINE</geographic>
    </subject>
    <classification authority="local">050</classification>
    <classification authority="local">080</classification>
    <relatedItem type="host">
      <titleInfo>
        <title>Transactions of the Royal Society of Tropical Medicine and Hygiene</title>
      </titleInfo>
      <part>
        <detail type="volume">
          <number>108</number>
        </detail>
        <detail type="volume">
          <number>5</number>
        </detail>
        <extent unit="pages">
          <list> 269-276</list>
        </extent>
      </part>
      <originInfo>
        <dateIssued>2014</dateIssued>
      </originInfo>
      <identifier type="issn">0035-9203</identifier>
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    <identifier type="uri">https://www.documentation.ird.fr/hor/fdi:010061978</identifier>
    <identifier type="doi">10.1093/trstmh/tru038</identifier>
    <identifier type="issn">0035-9203</identifier>
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      <recordCreationDate encoding="w3cdtf">2014-05-28</recordCreationDate>
      <recordChangeDate encoding="w3cdtf">2017-08-23</recordChangeDate>
      <recordIdentifier>fdi:010061978</recordIdentifier>
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        <languageTerm authority="iso639-2b">fre</languageTerm>
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