Dupouey J. auteur aut IRD Bichaud L. auteur aut IRD Ninove L. auteur aut IRD Zandotti C. auteur aut IRD Thirion Laurence auteur aut IRD De Lamballerie Xavier auteur aut IRD Charrel R. N. auteur aut IRD text journalArticle eng text/pdf born digital access Toscana virus (TOSV) is a neglected sandfly-borne pathogen in Mediterranean countries. Although discovered four decades ago, articles that describe the clinical aspects are scarce and consist mostly of case reports, with few series of cases. We studied retrospectively symptomatic TOSV infections in patients hospitalized in Marseille (France) from 2004 to 2011. Seventeen patients were classified as probable or confirmed cases. Fourteen cases (82%) occurred between June and September, and 3 cases in March, April and November. Two cases were potentially imported from Croatia and Tuscany. All patients presented with fever and neurological signs were observed such as aseptic meningitis (n = 6), muscular symptoms (n = 3), or encephalitis (n = 4). The outcome was always favorable. At the acute stage, anti TOSV IgM were observed in 14/17 patients, neutralization tests were positive for 3/8 patients, and RT-PCR confirmed TOSV infections in 5/8 CSF specimens. specialized Phlebovirus Arbovirus Emerging Meningitis Fever FRANCE 052 68 3 290-295 2014 0163-4453 https://www.documentation.ird.fr/hor/fdi:010061812 10.1016/j.jinf.2013.11.006 0163-4453 [F B010061812] https://www.documentation.ird.fr/hor/fdi:010061812 https://www.documentation.ird.fr/intranet/publi/2014/03/010061812.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2014-04-02 2017-08-23 fdi:010061812 fre