@article{fdi:010061347,
  title = {{G}enomic survey of pathogenicity determinants and {VNTR} markers in the cassava bacterial pathogen {X}anthomonas axonopodis pv. manihotis strain cio151},
  author = {{A}rrieta-{O}rtiz, {M}. {L}. and {R}odriguez, {L}. {M}. and {P}erez-{Q}uintero, {A}. {L}. and {P}oulin, {L}ucie and {D}iaz, {A}. {C}. and {A}rias {R}ojas, {N}. and {T}rujillo, {C}. and {R}estrepo {B}enavides, {M}. and {B}art, {R}. and {B}och, {J}. and {B}oureau, {T}. and {D}arrasse, {A}. and {D}avid, {P}. and {D}ugu{\'e} de {B}ernonville, {T}. and {F}ontanilla, {P}. and {G}agnevin, {L}. and {G}u{\'e}rin, {F}. and {J}acques, {M}. {A}. and {L}auber, {E}. and {L}efeuvre, {P}. and {M}edina, {C}. and {M}edina, {E}. and {M}ontenegro, {N}. and {M}unoz {B}odnar, {A}. and {N}oel, {L}. {D}. and {O}rtiz {Q}uinones, {J}. {F}. and {O}sorio, {D}. and {P}ardo, {C}. and {P}atil, {P}. {B}. and {P}oussier, {S}. and {P}ruvost, {O}. and {R}ob{\`e}ne-{S}oustrade, {I}. and {R}yan, {R}. {P}. and {T}abima, {J}. and {U}rrego {M}orales, {O}. {G}. and {V}erni{\`e}re, {C}. and {C}arrere, {S}. and {V}erdier, {V}al{\'e}rie and {S}zurek, {B}oris and {R}estrepo, {S}. and {L}opez, {C}. and {K}oebnik, {R}alf and {B}ernal, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{X}anthomonas axonopodis pv. manihotis ({X}am) is the causal agent of bacterial blight of cassava, which is among the main components of human diet in {A}frica and {S}outh {A}merica. {C}urrent information about the molecular pathogenicity factors involved in the infection process of this organism is limited. {P}revious studies in other bacteria in this genus suggest that advanced draft genome sequences are valuable resources for molecular studies on their interaction with plants and could provide valuable tools for diagnostics and detection. {H}ere we have generated the first manually annotated high-quality draft genome sequence of {X}am strain {CIO}151. {I}ts genomic structure is similar to that of other xanthomonads, especially {X}anthomonas euvesicatoria and {X}anthomonas citri pv. citri species. {S}everal putative pathogenicity factors were identified, including type {III} effectors, cell wall-degrading enzymes and clusters encoding protein secretion systems. {S}pecific characteristics in this genome include changes in the xanthomonadin cluster that could explain the lack of typical yellow color in all strains of this pathovar and the presence of 50 regions in the genome with atypical nucleotide composition. {T}he genome sequence was used to predict and evaluate 22 variable number of tandem repeat ({VNTR}) loci that were subsequently demonstrated as polymorphic in representative {X}am strains. {O}ur results demonstrate that {X}anthomonas axonopodis pv. manihotis strain {CIO}151 possesses ten clusters of pathogenicity factors conserved within the genus {X}anthomonas. {W}e report 126 genes that are potentially unique to {X}am, as well as potential horizontal transfer events in the history of the genome. {T}he relation of these regions with virulence and pathogenicity could explain several aspects of the biology of this pathogen, including its ability to colonize both vascular and non-vascular tissues of cassava plants. {A} set of 16 robust, polymorphic {VNTR} loci will be useful to develop a multi-locus {VNTR} analysis scheme for epidemiological surveillance of this disease.},
  keywords = {{AFRIQUE} ; {AMERIQUE} {DU} {SUD}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {8},
  numero = {11},
  pages = {e79704},
  ISSN = {1932-6203},
  year = {2013},
  DOI = {10.1371/journal.pone.0079704},
  URL = {https://www.documentation.ird.fr/hor/fdi:010061347},
}