Publications des scientifiques de l'IRD

Ayala Diego, Guerrero R. F., Kirkpatrick M. (2013). Reproductive isolation and local adaptation quantified for a chromosome inversion in a malaria mosquito. Evolution, 67 (4), 946-958. ISSN 0014-3820.

Titre du document
Reproductive isolation and local adaptation quantified for a chromosome inversion in a malaria mosquito
Année de publication
2013
Type de document
Article référencé dans le Web of Science WOS:000317133800003
Auteurs
Ayala Diego, Guerrero R. F., Kirkpatrick M.
Source
Evolution, 2013, 67 (4), 946-958 ISSN 0014-3820
Chromosome inversions have long been thought to be involved in speciation and local adaptation. We have little quantitative information, however, about the effects that inversion polymorphisms have on reproductive isolation and viability. Here we provide the first estimates from any organism for the total amount of reproductive isolation associated with an inversion segregating in natural populations. We sampled chromosomes from 751 mosquitoes of the malaria vector Anopheles funestus along a 1421 km transect in Cameroon that traverses savannah, highland, and rainforest ecological zones. We then developed a series of population genetic models that account for selection, migration, and assortative mating, and fit the models to the data using likelihood. Results from the best-fit models suggest there is strong local adaptation, with relative viabilities of homozygotes ranging from 25% to 130% compared to heterozygotes. Viabilities vary qualitatively between regions: the inversion is underdominant in the savannah, whereas in the highlands it is overdominant. The inversion is also implicated in strong assortative mating. In the savannah, the two homozygote forms show 92% reproductive isolation, suggesting that this one inversion can generate most of the genetic barriers needed for speciation.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
CAMEROUN
Localisation
Fonds IRD [F B010060813]
Identifiant IRD
fdi:010060813
Contact