@article{fdi:010060566,
  title = {{HIV} {T}ype 1 subtype {C} remains the predominant subtype in men having sex with men in {S}enegal},
  author = {{N}diaye, {H}. {D}. and {T}chiakpe, {E}. and {V}idal, {N}icole and {N}diaye, {O}. and {D}iop, {A}. {K}. and {P}eeters, {M}artine and {M}boup, {S}. and {T}oure-{K}ane, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{HIV}-1 epidemics are expanding among men who have sex with men in low-and middle-income countries. {T}o confirm and further explore preliminary data in {S}enegal, we aimed to determine 3 years after a first study the {HIV}-1 genetic diversity in three different viral regions. {F}rom 109 samples available in 2007, 93 were sequenced in gag, 77 in env, and 60 in pol. {P}hylogenetic analysis showed that subtype {C} predominated (38-52%), followed by {CRF}02_{AG} (30-40%), subtype {B} (13-17%), and {CRF}09_cpx (2.6-5%). {S}ubsubtype {A}3 and strains tightly linked to {CRF}43_02{G} were identified in env and gag, respectively, and 12% of the samples were unique recombinants. {S}ix transmission chains involving two to seven individuals were identified. {S}ome strains carried resistance mutations inside transmission chains. {T}his study confirmed the existence of a dual epidemic in {S}enegal and emphasized the need to strengthen prevention programs to avoid strains intermixing between low-risk women and high-risk men.},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{A}ids {R}esearch and {H}uman {R}etroviruses},
  volume = {29},
  numero = {9},
  pages = {1265--1272},
  ISSN = {0889-2229},
  year = {2013},
  DOI = {10.1089/aid.2013.0140},
  URL = {https://www.documentation.ird.fr/hor/fdi:010060566},
}