Doucouré Souleymane auteur aut IRD Cornélie Sylvie auteur aut IRD Patramool S. auteur aut IRD Mouchet François auteur aut IRD Demettre E. auteur aut IRD Seveno M. auteur aut IRD Dehecq J. S. auteur aut IRD Rutee H. auteur aut IRD Hervé Jean-Pierre auteur aut IRD Favier F. auteur aut IRD Missé Dorothée auteur aut IRD Gasque P. auteur aut IRD Remoué Franck auteur aut IRD text journalArticle eng text/pdf born digital access Study of the human antibody (Ab) response to Aedes salivary proteins can provide new biomarkers to evaluate human exposure to vector bites. The identification of genus-and/or species-specific proteins is necessary to improve the accuracy of biomarkers. We analysed Aedes albopictus immunogenic salivary proteins by 2D immunoproteomic technology and compared the profiles according to human individual exposure to Ae. albopictus or Ae. aegypti bites. Strong antigenicity to Ae. albopictus salivary proteins was detected in all individuals whatever the nature of Aedes exposure. Amongst these antigenic proteins, 68% are involved in blood feeding, including D7 protein family, adenosine deaminase, serpin and apyrase. This study provides an insight into the repertoire of Ae. albopictus immunogenic salivary proteins for the first time. specialized Ae. albopictus saliva immunogenic exposure biomarker 052 020 22 4 411-423 2013 0962-1075 https://www.documentation.ird.fr/hor/fdi:010060470 10.1111/imb.12032 0962-1075 [F B010060470] https://www.documentation.ird.fr/hor/fdi:010060470 https://www.documentation.ird.fr/intranet/publi/2013/08/010060470.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2013-09-03 2017-08-23 fdi:010060470 fre