<?xml version="1.0"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Gestational age-related changes in the peripheral blood cell composition of sub-Saharan African women</dc:title>
  <dc:creator>Ibitokou, S.</dc:creator>
  <dc:creator>/Brutus, Laurent</dc:creator>
  <dc:creator>Vianou, B.</dc:creator>
  <dc:creator>Oesterholt, M.</dc:creator>
  <dc:creator>Massougbodji, A.</dc:creator>
  <dc:creator>/Deloron, Philippe</dc:creator>
  <dc:creator>Troye-Blomberg, M.</dc:creator>
  <dc:creator>/Fievet, Nadine</dc:creator>
  <dc:creator>/Luty, Adrian</dc:creator>
  <dc:subject>Pregnancy</dc:subject>
  <dc:subject>Peripheral blood mononuclear cells</dc:subject>
  <dc:subject>African women</dc:subject>
  <dc:subject>Longitudinal cohort study</dc:subject>
  <dc:subject>Lymphocytes</dc:subject>
  <dc:subject>Antigen-presenting cells</dc:subject>
  <dc:description>Gestational age-related changes in the cellular composition of peripheral blood have not been described in sub-Saharan African settings. We conducted longitudinal cohort studies in Beninese and Tanzanian mothers with quantification of peripheral blood mononuclear cell-types ex vivo using flow cytometry. Between the second trimester and delivery the frequency of CD4(+) T cells declined significantly, contrasting with a non-significant increase in CD8(+) T cells, but no changes in T-regulatory, NK or NKT cell frequencies. Antigen-presenting cell profiles were also unaltered, although non-significant trends were evident. These changes resemble in some respects those reported during pregnancies in developed countries, but differ in others.</dc:description>
  <dc:date>2013</dc:date>
  <dc:type>text</dc:type>
  <dc:identifier>https://www.documentation.ird.fr/hor/fdi:010060425</dc:identifier>
  <dc:identifier>fdi:010060425</dc:identifier>
  <dc:identifier>Ibitokou S., Brutus Laurent, Vianou B., Oesterholt M., Massougbodji A., Deloron Philippe, Troye-Blomberg M., Fievet Nadine, Luty Adrian. Gestational age-related changes in the peripheral blood cell composition of sub-Saharan African women. 2013, 98 (1-2),  21-28</dc:identifier>
  <dc:language>EN</dc:language>
  <dc:coverage>AFRIQUE SUBSAHARIENNE</dc:coverage>
</oai_dc:dc>
