Namountougou M. auteur aut IRD Diabaté A. auteur aut IRD Etang J. auteur aut IRD Bass C. auteur aut IRD Sawadogo S. P. auteur aut IRD Gnankinié O. auteur aut IRD Baldet T. auteur aut IRD Martin T. auteur aut IRD Chandre Fabrice auteur aut IRD Simard Frédéric auteur aut IRD Dabiré R. K. auteur aut IRD text journalArticle eng text/pdf born digital access We investigated the occurrence of the L1014F and L1014S kdr mutations in malaria vector populations in Burkina Faso (West Africa). A cross-sectional survey was conducted at 10 sites all located in cotton cultivation areas which are assumed to be the major insecticide resistance selection foci in Burkina Faso. The hot ligation method was used to detect the two kdr mutations in field collected Anopheles gambiae s.l. samples. For the first time in Burkina Faso the L1014S mutation was identified in both M and S forms of An. gambiae s.s. populations collected from the site of Koupela in the central-eastern region at low frequency. Furthermore, the L1014S mutation was also found in one specimen of An. arabiensis collected from the Dano site. The data generated in this study provides additional evidence of the spread of the L1014S mutation into An. gambiae s.l. populations in West Africa. It is now important to evaluate the role of the L1014S mutation in the pyrethroid resistance phenotype and assess its potential impact on the efficacy of pyrethroid-based control measures in West Africa where several resistance mutations now coexist. specialized Anopheles gambiae s.l. L1014F and L1014S kdr Insecticide resistance Malaria Burkina Faso BURKINA FASO 052 125 2 123-127 2013 0001-706X https://www.documentation.ird.fr/hor/fdi:010058945 10.1016/j.actatropica.2012.10.012 0001-706X [F B010058945] https://www.documentation.ird.fr/hor/fdi:010058945 https://www.documentation.ird.fr/intranet/publi/2013/02/010058945.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2013-03-06 2017-08-23 fdi:010058945 fre