@article{fdi:010058850, title = {{P}atterns of genomic differentiation between ecologically differentiated {M} and {S} forms of {A}nopheles gambiae in {W}est and {C}entral {A}frica}, author = {{R}eidenbach, {K}. {R}. and {N}eafsey, {D}. {E}. and {C}ostantini, {C}arlo and {S}agnon, {N}. and {S}imard, {F}r{\'e}d{\'e}ric and {R}agland, {G}. {J}. and {E}gan, {S}. {P}. and {F}eder, {J}. {L}. and {M}uskavitch, {M}. {A}. {T}. and {B}esansky, {N}. {J}.}, editor = {}, language = {{ENG}}, abstract = {{A}nopheles gambiae {M} and {S} are thought to be undergoing ecological speciation by adapting to different larval habitats. {T}oward an improved understanding of the genetic determinants and evolutionary processes shaping their divergence, we used a 400,000 single-nucleotide polymorphism ({SNP}) genotyping array to characterize patterns of genomic differentiation between four geographically paired {M} and {S} population samples from {W}est and {C}entral {A}frica. {I}n keeping with recent studies based on more limited genomic or geographic sampling, divergence was not confined to a few isolated "speciation islands." {D}ivergence was both widespread across the genome and heterogeneous. {M}oreover, we find consistent patterns of genomic divergence across sampling sites and mutually exclusive clustering of {M} and {S} populations using genetic distances based on all 400,000 {SNP}s, implying that {M} and {S} are evolving collectively across the study area. {N}evertheless, the clustering of local {M} and {S} populations using genetic distances based on {SNP}s from genomic regions of low differentiation is consistent with recent gene flow and introgression. {T}o account for these data and reconcile apparent paradoxes in reported patterns of {M}-{S} genomic divergence and hybridization, we propose that extrinsic ecologically based postmating barriers vary in strength as environmental conditions fluctuate or change.}, keywords = {divergent selection ; genome scan ; introgression ; population genomics ; {SNP} genotyping ; speciation islands ; {AFRIQUE} {DE} {L}'{OUEST} ; {AFRIQUE} {CENTRALE}}, booktitle = {}, journal = {{G}enome {B}iology and {E}volution}, volume = {4}, numero = {12}, pages = {1202--1212}, ISSN = {1759-6653}, year = {2012}, DOI = {10.1093/gbe/evs095}, URL = {https://www.documentation.ird.fr/hor/fdi:010058850}, }