@article{fdi:010058233, title = {{U}pdate on the proteomics of major arthropod vectors of human and animal pathogens}, author = {{P}atramool, {S}. and {C}houmet, {V}. and {S}urasombatpattana, {P}. and {S}abatier, {L}. and {T}homas, {F}. and {T}hongrungkiat, {S}. and {R}abilloud, {T}. and {B}oulanger, {N}. and {B}iron, {D}. {G}. and {M}iss{\'e}, {D}oroth{\'e}e}, editor = {}, language = {{ENG}}, abstract = {{V}ector-borne diseases ({VBD}s) are defined as infectious diseases of humans and animals caused by pathogenic agents such as viruses, protists, bacteria, and helminths transmitted by the bite of blood-feeding arthropod ({BFA}) vectors. {VBD}s represent a major public health threat in endemic areas, generally subtropical zones, and many are considered to be neglected diseases. {G}enome sequencing of some arthropod vectors as well as modern proteomic and genomic technologies are expanding our knowledge of arthropodpathogen interactions. {T}his review describes the proteomic approaches that have been used to investigate diverse biological questions about arthropod vectors, including the interplay between vectors and pathogens. {P}roteomic studies have identified proteins and biochemical pathways that may be involved in molecular crosstalk in {BFA}-pathogen associations. {F}uture work can build upon this promising start and functional analyses coupled with interactome bioassays will be carried out to investigate the role of candidate peptides and proteins in {BFA}-human pathogen associations. {D}issection of the hostpathogen interactome will be key to understanding the strategies and biochemical pathways used by {BFA}s to cope with pathogens.}, keywords = {{H}ost-pathogen interaction ; {M}icrobiology ; {M}idgut ; {S}aliva ; {V}ector-borne diseases}, booktitle = {}, journal = {{P}roteomics}, volume = {12}, numero = {23-24}, pages = {3510--3523}, ISSN = {1615-9853}, year = {2012}, DOI = {10.1002/pmic.201200300}, URL = {https://www.documentation.ird.fr/hor/fdi:010058233}, }