@article{fdi:010057025,
  title = {{G}enetic structure and phylogeography of {A}edes aegypti, the dengue and yellow-fever mosquito vector in {B}olivia},
  author = {{P}aupy, {C}hristophe and {L}e {G}off, {G}ilbert and {B}rengues, {C}{\'e}cile and {G}uerra, {M}. and {R}evollo, {J}. and {S}imon, {Z}. {B}. and {H}erv{\'e}, {J}ean-{P}ierre and {F}ontenille, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{B}etween the 16th and 18th centuries, {A}edes aegypti ({D}iptera: {C}ulicidae), a mosquito native to {A}frica, invaded the {A}mericas, where it was successively responsible for the emergence of yellow fever ({YF}) and dengue ({DEN}). {T}he species was eradicated from numerous {A}merican countries in the mid-20th century, but re-invaded them in the 1970s and 1980s. {L}ittle is known about the precise identities of {A}e. aegypti populations which successively thrived in {S}outh {A}merica, or their relation with the epidemiological changes in patterns of {YF} and {DEN}. {W}e examined these questions in {B}olivia, where {A}e. aegypti, eradicated in 1943, re-appeared in the 1980s. {W}e assessed the genetic variability and population genetics of {A}e. aegypti samples in order to deduce their genetic structure and likely geographic origin. {U}sing a 21-population set covering {B}olivia, we analyzed the polymorphism at nine microsatellite loci and in two mitochondrial {DNA} regions ({COI} and {ND}4). {M}icrosatellite markers revealed a significant genetic structure among geographic populations ({F}-{ST} = 0.0627, {P} < 0.0001) in relation with the recent re-expansion of {A}e. aegypti in {B}olivia. {A}nalysis of mt{DNA} sequences revealed the existence of two genetic lineages, one dominant lineage recovered throughout {B}olivia, and the second restricted to rural localities in {S}outh {B}olivia. {P}hylogenic analysis indicated that this minority lineage was related to {W}est {A}frican {A}e. aegypti specimens. {I}n conclusion, our results suggested a temporal succession of {A}e. aegypti populations in {B}olivia, that potentially impacted the epidemiology of dengue and yellow fever.},
  keywords = {{A}edes aegypti ; {M}icrosatellite ; {M}itochondrial {DNA} ; {P}opulation genetics ; {B}olivia ; {BOLIVIE}},
  booktitle = {},
  journal = {{I}nfection {G}enetics and {E}volution},
  volume = {12},
  numero = {6},
  pages = {1260--1269},
  ISSN = {1567-1348},
  year = {2012},
  DOI = {10.1016/j.meegid.2012.04.012},
  URL = {https://www.documentation.ird.fr/hor/fdi:010057025},
}