Nsango S. E. auteur aut IRD Abate Luc auteur aut IRD Thoma M. auteur aut IRD Pompon J. auteur aut IRD Fraiture M. auteur aut IRD Rademacher A. auteur aut IRD Berry A. auteur aut IRD Awono-Ambene P. H. auteur aut IRD Levashina E. A. auteur aut IRD Morlais Isabelle auteur aut IRD text journalArticle eng text/pdf born digital access Mosquito infections with natural isolates of Plasmodium falciparum are notoriously variable and pose a problem for reliable evaluation of efficiency of transmission-blocking agents for malaria control interventions. Here, we show that monoclonal P. falciparum isolates produce higher parasite loads than mixed ones. Induction of the mosquito immune responses by wounding efficiently decreases Plasmodium numbers in monoclonal infections but fails to do so in infections with two or more parasite genotypes. Our results point to the parasites genetic complexity as a potentially crucial component of mosquito-parasite interactions. specialized Malaria Mosquito Vector biology Plasmodium COI Immunity Complement 052 42 6 589-595 2012 0020-7519 https://www.documentation.ird.fr/hor/fdi:010057014 10.1016/j.ijpara.2012.03.008 0020-7519 [F B010057014] https://www.documentation.ird.fr/hor/fdi:010057014 https://www.documentation.ird.fr/intranet/publi/2012/08/010057014.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2012-09-03 2020-07-13 fdi:010057014 fre