@article{fdi:010056991,
  title = {{S}ex ratio of {P}lasmodium falciparum gametocytes in inhabitants of {D}ielmo {S}enegal},
  author = {{R}obert, {V}incent and {S}okhna, {C}.{S}. and {R}ogier, {C}. and {A}riey, {F}. and {T}rape, {J}ean-{F}ran{\c{c}}ois},
  editor = {},
  language = {{ENG}},
  abstract = {{A}n epidemiological survey was conducted during a 4-month period of intense malaria transmission in {D}ielmo, a holoendemic {S}enegalese village. {T}wo thick blood smears per inhabitant were collected weekly. {T}he sex ratio of {P}las-
modium falciparum gametocytes (gamete precursors) was studied in 50 gametocyte carriers. {A}ll age classes were represented (mean 19.7 years ; range : 2 months-75 years) ; 42 (84 %) of them did not receive antimalarial treatment. {O}verall
668 thick smears were examined until 100 gametocytes had been counted or for 40 min. {A} total of 11 204 gametocytes were observed with a mean sex ratio of 0.346 (95 % {CI} 0.317-0.374), i.e. 2.89 females per 1 male. {A}mong the 284 thick
smears in which at least 10 gametocytes were observed, the mean percentage of male gametocytes was 27.8%, with a range of 0-82 %. {G}reat variability was observed between gametocyte carriers and also between thick smears from the same
gametocyte carrier. {A} multivariate analysis was performed which highlighted the fact that only 2 variables had a significant effect on the sex ratio. {A}naemia was associated with an increased percentage of males ({P}revalence {R}ate {R}atio [{PPR}] of male
gametocytes was multiplied by 1.65 if haematocrit rate <32 %) and a wave of gametocytes was associated with an increased percentage of female gametocytes ({PRR} was multiplied by 0.48 during the peak of gametocytaemia and for the 2 weeks
following this peak). {T}he variables without significant effect on sex ratio were: age, sex, clinical status and sickle cell trait status of the gametocyte carrier, density of asexual parasites, quinine treatment, and gametocyte density (when taking
account of its waves). {T}hese results are discussed in regard of possible differential production, mortality or sequestration of one gametocyte sex and selective advantages for the transmission of parasites.},
  keywords = {{PALUDISME} ; {AGENT} {PATHOGENE} ; {SEX} {RATIO} ; {SANG} ; {DENSITE} ; {GENOTYPE} ; {ANEMIE} ; {SENEGAL} ; {DIELMO}},
  booktitle = {},
  journal = {{P}arasitology},
  volume = {127},
  numero = {1},
  pages = {1--8},
  year = {2003},
  DOI = {10.1017/{S}0031182003003299},
  URL = {https://www.documentation.ird.fr/hor/fdi:010056991},
}