@article{fdi:010055872,
  title = {{T}he development of {PROQOL}-{HIV} : an international instrument to assess the health-related quality of life of persons living with {HIV}/{AIDS}},
  author = {{D}uracinsky, {M}. and {H}errmann, {S}. and {B}erzins, {B}. and {A}rmstrong, {A}. {R}. and {K}ohli, {R}. and {L}e {C}oeur, {S}ophie and {D}iouf, {A}. and {F}ournier, {I}. and {S}chechter, {M}. and {C}hassany, {O}.},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjectives: {H}ealth-related quality of life ({HRQL}) is an important outcome in {HIV}/{AIDS} infection and treatment. {H}owever, most existing {HIV}-{HRQL} instruments miss important issues (eg, sleeping problems, lipodystrophy). {T}hey were developed before highly active antiretroviral therapy (pre-{HAART}), and in a single language. {W}e sought to develop a contemporary {HIV}-{HRQL} instrument ({PROQOL}-{HIV}) in multiple languages that accounts for {HAART} treatment and side effects. {T}his article details the 3-stage content validation phase of {PROQOL}-{HIV}. {M}ethods: {I}n stage 1, we developed a conceptual model of {HIV}-{HRQL} and questionnaire item bank from thematic analysis of 152 patient interviews conducted simultaneously across 9 countries. {I}n stage 2, pilot items were selected by an expert panel to form the pilot instrument. {S}tage 3 involved linguistic validation and harmonization of selected items to form an equivalent instrument in 9 target languages. {R}esults: {A}nalysis of 3375 pages of interview text revealed 11 underlying themes: general health perception, social relationships, emotions, energy/fatigue, sleep, cognitive functioning, physical and daily activity, coping, future, symptoms, and treatment. {S}even issues new to {HIV}-{HRQL} measurement were subsumed by these themes: infection fears, future concerns, satisfaction with care, self-esteem problems, sleep problems, work disruption, and treatment issues. {O}f the 442 theme-related items banked, 70 items met the retention criteria and formed the pilot {PROQOL}-{HIV} instrument. {C}onclusions: {HIV} patients across 11 countries attributed a wide range of physical, mental, and social issues to their condition, many of which were not measured by existing {HIV}-{HRQL} instruments. {T}he pilot {PROQOL}-{HIV} instrument captures these issues, is sensitive to sociocultural context, disease stage, and {HAART}.},
  keywords = {{HIV} ; {AIDS} ; {HAART} ; quality of life ; health measurement instrument ; psychometrics},
  booktitle = {},
  journal = {{J}aids : {J}ournal of {A}cquired {I}mmune {D}eficiency {S}yndromes},
  volume = {59},
  numero = {5},
  pages = {498--505},
  ISSN = {1525-4135},
  year = {2012},
  DOI = {10.1097/{QAI}.0b013e318245cafe},
  URL = {https://www.documentation.ird.fr/hor/fdi:010055872},
}