Vittecoq Marion auteur aut IRD Elguero Eric auteur aut IRD Lafferty K. D. auteur aut IRD Roche Benjamin auteur aut IRD Brodeur J. auteur aut IRD Gauthier-Clerc M. auteur aut IRD Missé Dorothée auteur aut IRD Thomas F. auteur aut IRD text journalArticle eng text/pdf born digital access The incidence of adult brain cancer was previously shown to be higher in countries where the parasite Toxoplasma gondii is common, suggesting that this brain protozoan could potentially increase the risk of tumor formation. Using countries as replicates has, however, several potential confounding factors, particularly because detection rates vary with country wealth. Using an independent dataset entirely within France, we further establish the significance of the association between T. gondii and brain cancer and find additional demographic resolution. In adult age classes 55 years and older, regional mortality rates due to brain cancer correlated positively with the local seroprevalence of T. gondii. This effect was particularly strong for men. While this novel evidence of a significant statistical association between T. gondii infection and brain cancer does not demonstrate causation, these results suggest that investigations at the scale of the individual are merited. specialized Encephalon tumors Medical geography Malignancy Nervous system Latent toxoplasmosis 052 050 12 2 496-498 2012 1567-1348 https://www.documentation.ird.fr/hor/fdi:010055764 10.1016/j.meegid.2012.01.013 1567-1348 [F B010055764] https://www.documentation.ird.fr/hor/fdi:010055764 https://www.documentation.ird.fr/intranet/publi/2012/05/010055764.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2012-06-01 2017-08-23 fdi:010055764 fre