@article{fdi:010055764, title = {{B}rain cancer mortality rates increase with {T}oxoplasma gondii seroprevalence in {F}rance}, author = {{V}ittecoq, {M}arion and {E}lguero, {E}ric and {L}afferty, {K}. {D}. and {R}oche, {B}enjamin and {B}rodeur, {J}. and {G}authier-{C}lerc, {M}. and {M}iss{\'e}, {D}oroth{\'e}e and {T}homas, {F}.}, editor = {}, language = {{ENG}}, abstract = {{T}he incidence of adult brain cancer was previously shown to be higher in countries where the parasite {T}oxoplasma gondii is common, suggesting that this brain protozoan could potentially increase the risk of tumor formation. {U}sing countries as replicates has, however, several potential confounding factors, particularly because detection rates vary with country wealth. {U}sing an independent dataset entirely within {F}rance, we further establish the significance of the association between {T}. gondii and brain cancer and find additional demographic resolution. {I}n adult age classes 55 years and older, regional mortality rates due to brain cancer correlated positively with the local seroprevalence of {T}. gondii. {T}his effect was particularly strong for men. {W}hile this novel evidence of a significant statistical association between {T}. gondii infection and brain cancer does not demonstrate causation, these results suggest that investigations at the scale of the individual are merited.}, keywords = {{E}ncephalon tumors ; {M}edical geography ; {M}alignancy ; {N}ervous system ; {L}atent toxoplasmosis}, booktitle = {}, journal = {{I}nfection {G}enetics and {E}volution}, volume = {12}, numero = {2}, pages = {496--498}, ISSN = {1567-1348}, year = {2012}, DOI = {10.1016/j.meegid.2012.01.013}, URL = {https://www.documentation.ird.fr/hor/fdi:010055764}, }