@article{fdi:010054730,
  title = {{A} geographically explicit genetic model of worldwide human-settlement history},
  author = {{L}iu, {H}. and {P}rugnolle, {F}ranck and {M}anica, {A}. and {B}alloux, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}urrently available genetic and archaeological evidence is generally interpreted as supportive of a recent single origin of modern humans in {E}ast {A}frica. {H}owever, this is where the near consensus on human settlement history ends, and considerable uncertainty clouds any more detailed aspect of human colonization history. {H}ere, we present a dynamic genetic model of human settlement history coupled with explicit geographical distances from {E}ast {A}frica, the likely origin of modern humans. {W}e search for the best-supported parameter space by fitting our analytical prediction to genetic data that are based on 52 human populations analyzed at 783 autosomal microsatellite markers. {T}his framework allows us to jointly estimate the key parameters of the expansion of modern humans. {O}ur best estimates suggest an initial expansion of modern humans similar to 56,000 years ago from a small founding population of similar to 1,000 effective individuals. {O}ur model further points to high growth rates in newly colonized habitats. {T}he general fit of the model with the data is excellent. {T}his suggests that coupling analytical genetic models with explicit demography and geography provides a powerful tool for making inferences on human-settlement history.},
  keywords = {{AFRIQUE} {DE} {L}'{EST}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {H}uman {G}enetics},
  volume = {79},
  numero = {2},
  pages = {230--237},
  ISSN = {0002-9297},
  year = {2006},
  DOI = {10.1086/505436},
  URL = {https://www.documentation.ird.fr/hor/fdi:010054730},
}