@article{fdi:010054506, title = {{E}vidence for a correlation between systematics and bioactivity in {N}ew {C}aledonian {C}unoniaceae and {I}ts implications for screening and conservation}, author = {{P}illon, {Y}ohan and {F}ogliani, {B}.}, editor = {}, language = {{ENG}}, abstract = {{I}t is generally assumed that there is a good correlation between systematics and the secondary compounds found in plants. {H}owever because of the frequent homoplasy of chemical characters this has been difficult to test using statistical methods. {H}ere we applied two nonparametric tests on a published data set, where 50 species of {N}ew {C}aledonian {C}unoniaceae were screened for bioactivity against several pathogenic strains. {U}sing {M}oran's {I} index we showed that in two of nine tests against pathogenic strains there was a significantly higher similarity than expected in bioactivities between species belonging to the same genus and a significantly higher than expected dissimilarity in bioactivity between species belonging to different tribes. {W}hen considering the bioactivities against all pathogenic strains with {M}antel tests, we also found significant correlation between bioactivity and phylogenetic distance in two of four tests. {T}his has implications in screening and conservation. {S}earches for new molecules and bioactivity should preferentially be made on species spread across the tree of life. {T}here is also a need to preserve as much phylogenetic diversity as possible to make sure that the widest reservoir of natural compounds remains available for future generations.}, keywords = {}, booktitle = {}, journal = {{P}acific {S}cience}, volume = {63}, numero = {1}, pages = {97--103}, ISSN = {0030-8870}, year = {2009}, DOI = {10.2984/1534-6188(2009)63[97:{EFACBS}]2.0.{CO};2}, URL = {https://www.documentation.ird.fr/hor/fdi:010054506}, }