Ruiz-Castell M. auteur aut IRD Paco P. auteur aut IRD Barbieri F.L. auteur aut IRD Duprey Jean-Louis auteur aut IRD Forns J. auteur aut IRD Carsin A.E. auteur aut IRD Freydier R. auteur aut IRD Casiot C. auteur aut IRD Sunyer J. auteur aut IRD Gardon Jacques auteur aut IRD text journalArticle eng text/pdf born digital access This study evaluates the neurodevelopment of children living near contaminated mining industries during their first year of life. Participants from the city of Oruro (Bolivia) were prospectively recruited during pregnancy. Follow-up occurred between May 2007 and November 2009. Information about the socioeconomic status and medical history of the pregnant women were collected using questionnaires. Neurodevelopment was evaluated for 246 children using the Bayley Scales of Infant Development (BSID) at 10.5-12.5 months of age. Exposure to trace elements (Pb, As, Cd, Sb, Cs, Zn, Fe, Cu, Se, Rb, and Sr) during prenatal life was evaluated by testing maternal blood concentrations before delivery. Almost all measured levels were lower than the control limits. The blood lead concentration of pregnant women was low, considering the contaminated environmental context. The geometric mean was 1.76 mu g/dL (95% Cl; 1.68-1.84), a level comparable with those observed in non-contaminated areas. The only element found to be relatively elevated was antimony, with a geometric mean of 1.03 mu g/dL (95% Cl: 0.96-1.11). Our results suggest that women from this mining area were not highly exposed. The Bayley Scales of Infant Development (BSID) did not reveal mental or psychomotor abnormalities. Surprisingly, at the observed low levels, lead was positively associated with the children's BSID performance. specialized Child neurodevelopment BSID Trace metals Mining city Bolivia BOLIVIE 050 038 064 112 147-154 2012 0013-9351 https://www.documentation.ird.fr/hor/fdi:010054403 10.1016/j.envres.2011.12.001 0013-9351 [F B010054403] https://www.documentation.ird.fr/hor/fdi:010054403 https://www.documentation.ird.fr/intranet/publi/2012/03/010054403.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2012-04-04 2017-08-23 fdi:010054403 fre