@article{fdi:010054368,
  title = {{I}ncidence of adult brain cancers is higher in countries where the protozoan parasite {T}oxoplasma gondii is common},
  author = {{T}homas, {F}. and {L}afferty, {K}. {D}. and {B}rodeur, {J}. and {E}lguero, {E}ric and {G}authier-{C}lerc, {M}. and {M}iss{\'e}, {D}oroth{\'e}e},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e explored associations between the common protozoan parasite {T}oxoplasma gondii and brain cancers in human populations. {W}e predicted that {T}. gondii could increase the risk of brain cancer because it is a long-lived parasite that encysts in the brain, where it provokes inflammation and inhibits apoptosis. {W}e used a medical geography approach based on the national incidence of brain cancers and seroprevalence of {T}. gondii. {W}e corrected reports of incidence for national gross domestic product because wealth probably increases the ability to detect cancer. {W}e also included gender, cell phone use and latitude as variables in our initial models. {P}revalence of {T}. gondii explained 19 per cent of the residual variance in brain cancer incidence after controlling for the positive effects of gross domestic product and latitude among nations. {I}nfection with {T}. gondii was associated with a 1.8-fold increase in the risk of brain cancers across the range of {T}. gondii prevalence in our dataset (4-67%). {T}hese results, though correlational, suggest that {T}. gondii should be investigated further as a possible oncogenic pathogen of humans.},
  keywords = {{T}oxoplasma gondii ; brain cancer ; medical geography},
  booktitle = {},
  journal = {{B}iology {L}etters},
  volume = {8},
  numero = {1},
  pages = {101--103},
  ISSN = {1744-9561},
  year = {2012},
  DOI = {10.1098/rsbl.2011.0588},
  URL = {https://www.documentation.ird.fr/hor/fdi:010054368},
}