@article{fdi:010053910, title = {{E}mergence of divergent {Z}aire ebola virus strains in {D}emocratic {R}epublic of the {C}ongo in 2007 and 2008}, author = {{G}rard, {G}. and {B}iek, {R}. and {T}amfum, {J}. {J}. {M}. and {F}air, {J}. and {W}olfe, {N}. and {F}ormenty, {P}. and {P}aweska, {J}. and {L}eroy, {E}ric}, editor = {}, language = {{ENG}}, abstract = {{M}ethods. {V}iruses of each outbreak were isolated and the full-length genomes were characterized. {P}hylogenetic analysis was then undertaken to characterize the relationships with previously described viruses. {R}esults. {T}he 2 {L}uebo viruses are nearly identical but are not related to lineage {A} viruses known in {DRC} or to descendants of the lineage {B} viruses encountered in the {G}abon-{R}epublic of the {C}ongo area, with which they do, however, share a common ancestor. {C}onclusions. {O}ur findings strongly suggest that the {L}uebo 2007 outbreak did not result from viral spread from previously identified foci but from an independent viral emergence. {T}he previously identified epidemiological link with migratory bat species known to carry {Z}aire ebolavirus {RNA} support the hypothesis of viral spillover from this widely dispersed reservoir. {T}he high level of similarity between the {L}uebo2007 and {L}uebo2008 viruses suggests that local wildlife populations (most likely bats) became infected and allowed local viral persistence and reemergence from year to year.}, keywords = {}, booktitle = {}, journal = {{J}ournal of {I}nfectious {D}iseases}, volume = {204}, numero = {{S}uppl. 3}, pages = {{S}776--{S}784}, ISSN = {0022-1899}, year = {2011}, DOI = {10.1093/infdis/jir364}, URL = {https://www.documentation.ird.fr/hor/fdi:010053910}, }