%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Maganga, G. D.
%A Bourgarel, M.
%A Ella, G. E.
%A Drexler, J. F.
%A Gonzalez, Jean-Paul
%A Drosten, C.
%A Leroy, Eric
%T Is Marburg virus enzootic in Gabon ?
%D 2011
%L fdi:010053909
%G ENG
%J Journal of Infectious Diseases
%@ 0022-1899
%M ISI:000295991400008
%N Suppl. 3
%P S800-S803
%R 10.1093/infdis/jir358
%U https://www.documentation.ird.fr/hor/fdi:010053909
%> https://www.documentation.ird.fr/intranet/publi/2011/11/010053909.pdf
%V 204
%W Horizon (IRD)
%X Marburg virus (MARV) nucleic acid was detected in Rousettus aegyptiacus bats in 2005 and 2006 in the midwest and southeast of Gabon. In this study we used MARV-specific real-time reverse-transcription polyermase chain reaction (RT-PCR) and MARV-specific nested RT-PCR assay to screen 1257 bats caught during July 2009, December 2009, and June 2010 in 3 caves situated in northern Gabon. Nine specimens tested positive by the real-time assay, with cycle threshold values ranging from 35 to 39, of which only 1 R. aegyptiacus specimen collected in 2009 was positive in the nested VP35 RT-PCR assay. Together with MARV-positive bats in the south and west found in 2005 and 2006, confirmation of phylogenetically closely related MARV-positive bats 5 years later and in northern Gabon suggests that MARV is now enzootic in Gabon and emphasizes the importance of long-term monitoring of bat populations and human-bat interfaces.
%$ 052