%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Le Goff, Gilbert %A Revollo, J. %A Guerra, M. %A Cruz, M. %A Simon, Z. B. %A Roca, Y. %A Flores, J.V. %A Hervé, Jean-Pierre %T Natural vertical transmission of dengue viruses by Aedes aegypti in Bolivia %D 2011 %L fdi:010053896 %G ENG %J Parasite : Journal de la Société Française de Parasitologie %@ 1252-607X %K Aedes aegypti ; vertical transmission ; dengue virus ; PCR %K BOLIVIE %M ISI:000295608900011 %N 3 %P 277-280 %U https://www.documentation.ird.fr/hor/fdi:010053896 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers17-10/010053896.pdf %V 18 %W Horizon (IRD) %X The natural transmission of dengue virus from an infected female mosquito to its progeny, namely the vertical transmission, was researched in wild caught Aedes aegypti during an important outbreak in the town of Santa Cruz de la Sierra, Bolivia. Mosquitoes were collected at the preimaginal stages (eggs, larvae and pupae) then reared up to adult stage for viral detection using molecular methods. Dengue virus serotypes 1 and 3 were found to be co-circulating with significant higher prevalence in male than in female mosquitoes. Of the 97 pools of Ae. aegypti (n = 635 male and 748 female specimens) screened, 14 pools, collected in February-May in 2007, were found positive for dengue virus infection: five DEN-1 and nine DEN-3. The average true infection rate (TIR) and minimum infection rate (MIR) were respectively 1.08 % and 1.01 %. These observations suggest that vertical transmission of dengue virus may be detected in vectors at the peak of an outbreak as well as several months before an epidemic occurs in human population. %$ 052